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其他產(chǎn)品
其他產(chǎn)品

Anti-caspase-3 Rabbit pAb

規(guī)格：PN0054

價(jià)格：1300元/10 ul，4900元/100 ul

產(chǎn)品特性

產(chǎn)品信息

抗體來源

Rabbit

克隆類型

Monoclonal

交叉反應(yīng)

Mouse, Rat, Human

產(chǎn)品應(yīng)用

WB 1:2000 IHC 1:1000 IP 1:80 

理論分子量

32kDa

細(xì)胞定位

細(xì)胞質(zhì)

性    狀

Liquid

濃    度

濃度范圍 10 μl 濃度為 1.519 - 1.6 mg/ml

濃度范圍 100 μl 濃度為 1.519 - 1.577 mg/ml

 

免 疫 原

Recombinant fragment. This information is

proprietary to Abcam and/or its suppliers.

亞    型

IgG

純化方法

Protein A purified

緩 沖 液

pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 0.05% BSA, 40% Glycerol (glycerin, glycerine)

保存條件

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

注意事項(xiàng)

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


背 景

Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp--Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.